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Robert Fox Jr., 17, of the 700 block of Magnolia Street in Sanford, was arrested and charged with first-degree murder Saturday.
On Friday, police announced that three suspects have been arrested in connection with the shooting that police described as drug-related:
Jontrell Orlando Wilson, 23, of the 3600 block of Renee Drive in Sanford, was arrested and charged with first-degree murder.
Shakur Antonio Sellers, 24, of the 2600 block of Mt. Pisgah Church Road in Sanford, was arrested and charged with first-degree murder.
Latavious Kwame McIver, 28, of the 500 block of Pineland Street in Sanford, was arrested and charged with first-degree murder.
All four suspects are being held in the Lee County Jail under no bond.
They are all scheduled to appear in court Monday.
Sanford police respond to deadly shooting
The victim was identified as Dirk Anthony Lequia, 30, of Palmetto, Florida.