The train was stopped in the area of West Cabarrus Street and South Harrington Street while police investigated.
The incident happened around 7:30 a.m. when Raleigh police and other first responders were dispatched to the train tracks. West Cabarrus Street between Dawson and West Streets was temporarily shut down.
The woman, described by police as a pedestrian, was not identified.
On October 7, a man died after being hit and killed by an Amtrak train in Raleigh between Hammond Road and Garner Road.
A 47-year-old man was killed by a train in Durham on September 27.