The Conclave is now underway, at least, in ceremony.
Mass marking the start of the process came to a close Wednesday in the Vatican and hundreds of people poured into St. Peter's Square.
The Vatican released video of cardinals, 220 of them, processing down the main aisle inside St. Peter's Basilica.
This Mass, in particular, was meant to pray for the 133 voting cardinals who will be choosing the next pope. The dean of the College of Cardinals asked for prayers for the cardinals as they take on this weighty decision.
The Vatican estimates roughly 250,000 people have made the pilgrimage here to Rome to witness the experience of the Conclave in what way they can from the outside.
An American priest flew in to pray for the cardinals.
"Well the prayers and the scripture readings were such that, basically, inviting the Holy Spirit to be present and to be with the cardinals as they prepared to gather in the Sistine Chapel in just a little while and pray that the Holy Spirit helps them to choose a successor to St. Peter," Father Bill Champlin said.
Father Thomas Reese, senior religious analyst for the Religious News Service, shared about what he believes cardinals will be considering.
"I think is looking for three things in a candidate. First, does this man agree with me on the issues facing the church and the direction the church should go in. Secondly, is this somebody I have a good relationship with, because, you know, after he becomes pope, I want to be able to talk to him. I want to listen to me. I want to have influence in this next papacy, And then thirdly, he is going to look for someone who will go over well in my part of the world."
Cardinals will now take the oath of secrecy late Wednesday afternoon before they're locked in the Sistine Chapel. They will take just one round of votes Wednesday around 5 p.m. Rome time, so the first smoke signals from the Sistine Chapel will come sometime in the evening.
This Mass was meant to pray for the 133 voting cardinals who will be choosing the next pope.
Michael Canaris, who's an Associate Professor at Loyola University Chicago, talks about the papal conclave.