Fantasy Football Daily Notes: Christian McCaffrey traded to 49ers, RBBC to replace him in Carolina

Read ESPN's fantasy football Daily Notes every weekday to stay caught up on the news you need to know and get a head start on the fantasy football content coming today and tomorrow to ESPN.com and the ESPN Fantasy App. Here are your fantasy headlines for Friday, Oct. 21.

The news: ESPN's Adam Schefter reported that the Panthers are trading RB Christian McCaffrey to the 49ers for draft picks.

What it means in fantasy: As compensation, the Panthers will receive second-, third- and fourth-round draft picks in the 2023 NFL draft, along with a fifth-round pick in 2024. McCaffrey is now part of Kyle Shanahan's fantasy-friendly offense in San Francisco that leans heavily on running backs as rushers and receivers out of the backfield. It will be a breath of fresh air for McCaffrey, considering the Panthers ranked last in the league in total yards per game. As soon as he takes the field, he can be considered a high-end RB1 with a shot at finishing as fantasy's most valuable player for the season.

Going deeper: After playing in all 16 games in each of his first three NFL seasons, McCaffrey was limited byinjuries to just 10 combined games in 2020 and 2021. However, he's been very productive when on the field. McCaffrey has averaged 19.6 touches and 22.2 fantasy points per game in his career.

The news: Panthers RBs D'Onta Foreman and Chuba Hubbard are expected to form a committee after Christian McCaffrey's departure.

What it means in fantasy: To be candid, I believe Foreman will lead the Panthers' committee ultimately but Hubbard will be involved as well. Carolina signed Foreman as a free agent from the Titans earlier this year. The Panthers didn't seem to be completely sold on Hubbard's 10-game stint as starter last year when McCaffrey missed time. While McCaffrey was out, Hubbard rushed for 514 yards and four touchdowns in 10 games. Additionally, he caught 19 passes for 110 yards and a touchdown. Filling in for Derrick Henry when he suffered a foot injury in Week 8 last season, Foreman had success with the Titans. He finished the season with 133 rushing attempts for 566 yards and three touchdowns, as well as nine receptions for 123 yards. Hubbard (96.5%) and Foreman (95.8%) are available in a high percentage of ESPN leagues. Both are on the flex radar for a Carolina offense that ranks last in the NFL in total yards per game.

The news: ESPN's Jeremy Fowler reported that WR DJ Moore is viewed as a "foundational piece to the roster."

What it means in fantasy: Moore is unlikely to be traded as the deadline approaches, despite multiple calls from other teams. Moore has been negatively impacted by the Panthers' offense, which isn't a fantasy football bonanza. A trade would significantly improve his fantasy outlook. This season, Moore has averaged 7.3 targets and 8.4 fantasy points. He was the WR15 in our draft trends this summer. Even as a flex option, Moore is difficult to trust.

The news: Cardinals WR Rondale Moore caught one of two targets for 31 yards against the Saints.

What it means in fantasy: As Marquise Brown is out for the immediate future with a foot injury, Moore was expected to play a more prominent role in the Cardinals' passing game. Over the past two games, Moore has caught 13 of 18 targets for 117 receiving yards. In his first game back after serving his suspension, DeAndre Hopkinshalted that positive momentum. He caught 10 of 14 targets for 103 receiving yards. In Week 8 against the Vikings, fantasy managers will have a hard time trusting Moore in their lineups.

Going deeper: This was the second time Hopkins had 10 receptions for 100 or more yards in his first game of a season. Over the past 20 seasons, only Hopkins, Davante Adams, Michael Thomas, Andre Johnson and Anquan Boldin have done that multiple times.

The news: Patriots RB Damien Harris practiced in full Thursday.

What it means in fantasy: Harris is dealing with a hamstring injury. After missing last week's game against the Browns, he seems on track to play Monday night against the Bears. Depending on how healthy Harris is, he will likely cut into Rhamondre Stevenson's snaps and opportunity share. Stevenson can still be inserted into fantasy lineups as an RB2.

The news: Seahawks WR Tyler Lockett missed practice for a second consecutive day as he deals with a hamstring injury.

What it means in fantasy: The Seahawks might be without Lockett for their matchup against the Chargers. The receiver has missed only two games in his career, and one was the final game of 2016 after breaking his leg. Lockett's status should be monitored by fantasy managers on Friday and likely into the weekend. Should Lockett not be able to go, Dee Eskridge and Marquise Goodwin will step up.

The news: Ravens RB J.K. Dobbins did not practice Thursday with a knee injury.

What it means in fantasy: Dobbins' knee tightened up against the Giants last week. It is possible that he will miss Sunday's game against the Browns after two consecutive DNPs. In the event he is inactive, fantasy managers should turn to Kenyan Drake, who filled in for Dobbins last week and finished with 19.7 fantasy points. Drake is still available in 82% of ESPN leagues. Gus Edwards is also close to returning from injured reserve. When he becomes active, he'll have a role in the backfield.

The news: Raiders TE Darren Waller missed practice for a second consecutive day with a hamstring injury.

What it means in fantasy: This is not good news for Waller, especially coming out of a bye week. There's a good chance he'll miss this week's game against the Texans. Backup tight end Foster Moreau is very capable of filling the void. He's a great contingency plan for fantasy managers who have Waller on their rosters.

The news: ESPN's Rich Cimini reports that WR Elijah Moore will be inactive for Week 7 against the Broncos after he requested a trade.

What it means in fantasy: Moore is frustrated by his lack of targets, but the Jets are not considering a trade as the deadline is quickly approaching. Moore has been targeted only 29 times this season. His trade demand "didn't sit well with the Jets." Moore's absence opens the door for Corey Davis to have a high floor against the Broncos since Zach Wilson has a strong rapport with him.

Going deeper: Davis leads the Jets with 351 receiving yards on 19 catches, 17 of which were for first downs or touchdowns.

The news:WR Hunter Renfrow did not practice Thursday with a hip injury.

What it means in fantasy: The report came as a surprise. Fantasy managers should pivot to Mack Hollins if Renfrow is ruled out, since Hollins is still available in 93% of ESPN leagues. In the two games earlier this season when Hollins had eight or more targets, he finished with a combined 41.5 fantasy points.

The news: Ravens TE Mark Andrews missed practice on consecutive days for rest purposes.

What it means in fantasy: Coach John Harbaugh has publicly stated that these are rest days for Andrews, but he's also dealing with a knee injury. I believe Andrews will play against the Browns on Sunday. However, were Andrews unable to play, Ravens tight end Isaiah Likely would be an intriguing streamer. Cade Otton and Evan Engram should also be considered. WR Rashod Bateman is on track to return this week after dealing with a foot injury. After Week 6's loss to the Giants, offensive coordinator Greg Roman noted that Devin Duvernay should be more involved; this would be even more likely if Andrews were ruled out.

Today on ESPN.com/Fantasy and in the ESPN Fantasy App

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Fantasy Focus Podcast:Daniel Dopp, Stephania Bell and Mike Clay react to the massive Christian McCaffrey trade before previewing everything you need to know for Week 7 including key injury updates, lineup locks, if you can start Brady & much more! Watch

Sunday:

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Fantasy Football Now: Sunday at 10 a.m. ET on ESPN2

In case you missed it:

Field Yates' Fantasy Field Pass for Week 7: How will Dak, Tua, Hopkins fare in return to action?

Mike Clay's TNF Playbook: Saints vs. Cardinals

Tristan H. Cockcroft's positional Matchup Map

Matt Bowen's fantasy film room

Al Zeidenfeld's DFS Best Buys for Week 7

Fantasy Focus podcast:Field Yates, Mike Clay and Daniel Dopp preview a friendlier "Thursday Night Football" for fantasy before dishing out the WRs who have great matchups and the WRs you might need to bench. Then, Adam Schefter joins to talk the storylines to watch in Week 7, including who needs to be on your radar for a late-season push. Listen | Watch