Further details about the cases are not being released at this time.
NC State Student Health Services say they are working with the North Carolina Department of Health and Human Services and Wake County public health officials to combat with the illness.
The university says it has notified individuals who are enrolled in classes with the students who were diagnosed with H1N1 influenza to monitor themselves for flu symptoms.
Officials say symptoms could include: fever over 100 degrees, respiratory symptoms, such as cough and sore throat, runny or stuffy nose, and diarrhea or vomiting.
An e-mail alert was also sent to the campus community, including employees of the university.