Sheriff's Lt. Greg Turner says Hannah Emmaline Williams, of Sanford, N.C., was killed when the train struck her Thursday night.
Julianne Ashbaugh, of Temple, Ga., was hospitalized for critical injuries suffered when she fell from the trestle onto the ground.
Eighteen-year-old Patrick Marshall of Yorktown Virginia, 19-year-old Javier David Duque of Arlington Texas and 18-year-old Kaitlyn Hermening of Mosinee Wisconsin were treated for minor injuries.
Two of the survivors jumped to a nearby piling to escape the train, and another hung below the tracks by his arms.
Authorities told The News & Advance that the students were 130 feet from one end of the bridge when the Norfolk Southern train arrived.