The home is located on County Line, just inside Johnston County near the Harnett County line.
Crews were called to the home shortly after 2 a.m. Saturday.
An eyewitness told ABC11 he drove by when the fire was at its peak.
"I seen flames. I mean, they were reaching 50, 60 feet up in the air," Larry Parker said. "It was coming across the grass and then the power line burned, fell from the house, and the SUV caught on fire. I waited until the fire department came."
The home, which friends say pre-dates the Civil War and had been in the family for several generations, is a complete loss. The blaze also damaged the siding to the next door neighbor's home.
Both bodies were sent to the county medical examiner, but the names of the victims have not been released.
Officials have not yet determined the cause of the fire, but authorities are not calling it suspicious.