Demoraea Fennell was found shot just after 3 a.m. November 1 in the 400-block of Pilot Street - off Fayetteville Street.
He later died at Duke University Hospital.
Jose Anthony Morales, 50, of Durham was arrested and charged with murder in connection with the case, police announced Monday.
On November 14, police said 25-year-old Jaquinta Antanette Cole was charged with murder and felony conspiracy. Nikee Lamar Black, 26, was charged with felony conspiracy.
Cole and Black were both arrested in Monroe, Louisiana and brought back to Durham.
All three are being held without bond.
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