The project will add new sidewalks, turn lanes, and upgraded intersections and crossings.
The agency previously said construction would be finished in time for the 2025 North Carolina State Fair.
"We know it's going to be an inconvenience and we just ask everyone to, you know, remain patient," said Mayor Jacques Gilbert.
The crash also involved five other vehicles near Exit 186.
Right now, all traffic on I-40 in western North Carolina is traveling on two lanes after the other two lanes were washed out by flooding.
Starting Monday, crews will start building a new bridge for Beryl Road as part of the I-440 improvements project.