Those who are affected will be notified by September 3.
Atkinson said some of the displaced employees will have the opportunity to serve in another capacity within the WakeMed system. Also, there will be opportunities in Raleigh's new patient tower.
In addition to job cuts, WakMed will offset its loss of funding with reduced departmental spending in areas such as marketing, advertising and non-clinical equipment and expenses.
WakeMed employs 7,576 people.