The state Department of Transportation says construction is suspended until 9 a.m. Tuesday.
Both directions of Interstate 40 in Greensboro are reduced to two lanes between mile marker 213 and 214 due to construction of the Bridford Parkway Bridge.
In eastern North Carolina, U.S. 17 in Windsor is reduced to one lane on the Cashie River Bridge due to construction and trucks are restricted on the route.
Raleigh's Glenwood Avenue will have closures from Five Points to Wade Avenue to replace concrete.
In addition to these projects, the department reminds motorists traveling on westbound I-40 in Haywood County to expect delays over the holiday weekend.
Meanwhile, as travelers head to their decisions the Highway Patrol has "Operation Firecracker" underway. More troopers will be on interstates, highways and major four-lane roads in an effort to cut down on dangerous driving.