Continental Airlines and US Airways will begin operating from Concourse D.
The first phase of the terminal, which includes Concourse C, opened in 2008.
The terminal features 36 gates and 40 shops and restaurants - including Jason’s Deli, Five Guys Burgers & Fries and Flavours, a gourmet market.
New shops that will open on Sunday include Brighton Collectibles, PGA Tour Shop, Hudson News and 2nd Ed. Booksellers.
In addition to Continental and US Airways, the following airlines and their commuter partners will operate from Terminal 2: Air Canada, American, Delta, Frontier, United and Charter Express.
Southwest, AirTran and JetBlue will continue to operate from Terminal 1.