Deputies said 29-year old Ronald Joseph Guilette got into a verbal and physical domestic dispute with the woman in the front yard of their home.
During the fight, Guilette allegedly got into his truck and backed out of the driveway, and over his wife who was standing in the roadway.
The woman is being treated for a concussion, a spine fracture, and a broken hand - along with multiple lacerations - at Cape Fear Valley Medical Center.
Guilette is charged with assault with a deadly weapon. Bond was set at $5,000.