The Canes will play the Nashville Predators to open the playoffs. It will be the first time the two teams have met in the postseason.
Game 1 will be at 8 p.m. Monday at PNC Arena, where the Canes are 26-17 all-time in the postseason.
The Hurricanes are making their third consecutive playoff appearance for the first time since relocating to North Carolina in 1997.
Game 2 will be Wednesday in PNC Arena, also at 8 p.m.
The series shifts to Nashville on May 21 for a 7 p.m. game and Game 4 is set for May 23 in Nashville. Game time has not been determined.
If a Game 5 is needed, it would be May 25 in Raleigh. A potential Game 6 would be May 27 in Nashville.
If the series goes the distance, a deciding Game 7 would be held May 29 at PNC Arena.