Because of Alzheimer's she no longer recognizes her son, but she is clearly moved by his kindness.
"I don't know where we live, I don't know anything..." she says during his song.
But Joe smiles, reassures her that it's all OK and tells her that he loves her.
Joe said he was at first apprehensive about posting the video because it showed his mom at her worst.
But he says he did it to promote awareness about the ravages of Alzheimer's and so that his mom could bring a smile to someone else's face one more time.
VIDEO: Watch the full video here
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