Officers arrived around 5 p.m. to Target on Cox Road after someone reported a theft at the store.
Police tried to stop the suspect's car in the Target parking lot, but the driver, 38-year-old Thomas Kirkland, escaped and drove the wrong way on East Franklin Boulevard.
Kirkland then crashed head-on into a Dodge Avenger at an intersection. Kirkland's passenger, Deborah Patterson, 62, died in the crash.
Kirkland faces multiple charges, including misdemeanor death by motor vehicle, felony flee to elude arrest and felony larceny.
Read more from WSOC.