Police said around 1:30 p.m., a man was shot in the chest after a group of men was seen arguing in front of a home near the intersection of Durham and Hobbs Street.
According to Clayton police, the man fled in a black Yukon SUV and veered off the road, through a field and crashed into a building next to a Speedway gas station on Powhatan Road.
The man got out of the SUV, stumbled toward the gas station and then collapsed.
Emergency responders worked to save him but he was pronounced dead at the scene a short time later.
The victim was identified Friday by police as Darrius Pierre Lassiter, 29, of Apex.
Jairus Leshon Anderson, 18, of Raleigh was taken into custody by Clayton Police and is being charged with homicide in the shooting. A juvenile female is also in custody.
Police are still searching for a third suspect.
Video from Chopper 11 HD showed several marked and unmarked police cars, as well as many officers, outside the home shortly after the shooting, some with guns raised.
"The biggest concern that we have right now is that there's a lot of ground between Durham Street and (the Speedway)," Clayton Police Chief Blair Myhand told ABC11 on Thursday. "We have evidence in the field behind us that came out of the vehicle so we're looking to see what might have been scattered along 70 all the way up here."
The chief asked residents traveling in that stretch to look out for debris.
"I would ask that the public, if they come upon something that is either bloody or a gun or anything like that laying on the side of Highway 70 between Powhatan Road and Durham Street to call the police immediately," Myhand said.