Police said a 2004 Nissan Maxima driven by Marcus Rogers, 19, ran off the right side of the road, then went out of control, struck a ditch, flipped over numerous times and landed in a swarm of trees and thick weeds.
Police say the force of the crash threw all of the victims from the vehicle. Rogers was the only one to survive the crash.
Eyewitness News originally reported Rogers died in the wreck, but that information was incorrect.
According to Durham police spokesperson Kammie Michael, Rogers is in critical condition at Duke University Hospital.
Michael said investigators received incorrect information Tuesday night when they were told Rogers died from his injuries.
Destinee Taylor, 16, and 22-year-old Demonte Antwann Cissell were pronounced dead at the scene.
Shaunte Shephard, one of Roger's friends, said he is a quiet guy who opens up once you get to know him.Taylor's cousin Keshaunna Green said she last saw her earlier in the day during the tenth grader's first day of school at Hillside High.
"She walked up to me cause she saw me first and we smiled, gave each other hugs," Green said. "Just so happy like and that's how she should be remembered as a happy person."
"She was joyful, she was just … she liked to have fun," Taylor's grandfather Tony Raye Vaughn said. "Put it to you that way, she loved having fun."
Authorities said speed was a factor in the accident.
Chopper 11 HD was over the scene as authorities investigated the crash.
The accident shut down Old Oxford Highway near Craven Street for about three hours while Durham police, sheriff's deputies and fire fighters searched for the victims and removed the car.
Officials told Eyewitness News they found a car seat among debris from the car scattered over the wide area.
EMS crews searched to make sure there was not a child in the car at the time of the crash, but they never found one.