The driver of the car - 18-year-old Timothy Burnett - was rushed to the hospital, but his condition was not known immediately known. A relative said the teen was complaining of chest pains. It's not clear if those came before or after the impact.
A Wake County Public Schools spokesperson said the bus was headed to Wake Forest-Rolesville High School when it was rear-ended.
Three students in addition to Burnett were taken to the hospital with minor injuries. There were a total of 21 students on the bus.
Burnett was charged with failure to reduce speed to avoid a collision.