High led police through Knightdale and onto Interstate 540.
Authorities say the Mustang fled from the scene going about 55 mph.
The chase ended between Louisburg Road and Capitol Boulevard in Raleigh.
No one was seriously hurt, but police say the woman did try to run over an officer in Knightdale.
As High entered Knightdale, an Officer deployed spike strips to try and deflate the car's tires. Once she saw the spikes Police say High swerved at a Knightdale Officer and tried to hit him as she drove by.
A second Knightdale Officer then deployed a new set of spike strips that were successful in deflating two of the Mustang's four tires.
Even though two of her tires were deflated Officers say High kept driving.
Authorities continued the chase after several of the attempts made by law enforcement Officer's failed to make her stop. Despite two deflated tires, High kept driving to avoid Police. As High continued the chase onto Interstate 5-40, she hit a Wake County Sheriff's patrol car.
The chase ended after a Wake County Sheriff's Deputy used his patrol car to force High to stop.
High was taken into custody and transported to Wake Medical Center for evaluation.
She is being charged with Felony Speeding to Elude by Zebulon Police Department, attempted assault with a deadly weapon on a law Enforcement Officer by Knightdale Police Department
High could face even more charges from the Wake County Sheriff's Office.