The Cumberland County Sheriff's Office said in a news release that 19-year-old Terrell Orlando Boykin died at Cape Fear Valley Medical Center Monday.
Twenty-three-year-old Rodriguez Odell Harris died Sunday morning.
Both men were hit by gunfire at a home at 3921 Donna Street around 4:20 a.m. Sunday.
Deputies are investigating.
Anyone with information is urged to contact the Cumberland County Sheriff's Office at (910) 323-1500.