The school said freshman Megan Baab died in an accident on US Highway 221 in Altamont, N.C.
According to reports, Baab, 19, was riding north when a southbound truck crossed the centerline and hit her. She was airlifted to Johnson City Medical Center, but was pronounced dead soon after arrival.
Baab, a native of Euless, Texas, represented Lees-McRae at the USA Cycling National Championships.
"We all remember Megan as a bright and bubbly member of our campus community," said President Barry Buxton in a statement. "She always had a smile on her face and a friendly word to say. Her contributions to our campus were noteworthy, even though we were only able to share a single semester with her. We send our most heartfelt condolences to her family and friends in Texas and keep them in our thoughts and prayers."