Police arrested 37-year-old Caimen Leigh Ruff and 49-year-old Mitchell James Jareo, both of the 1100 block of Chamberwell Avenue.
Officials were executing a narcotics search warrant at the home when they discovered around 338 plants, weighing more than 45 lbs.
Adult marijuana plants can produce as much as two pounds of marijuana and each plant has an estimated value of $2,500. By employing this formula, police estimate the street value of the 338 seized marijuana plants to be approximately $845,000.
Officers also found additional marijuana packaged for sale and delivery, along with an assortment of drug paraphernalia, including high intensity lights, power inventors, thermal greenhouses, drying racks, irrigation supplies, fans, and humidifiers.
According to police, Ruff and Jareo had constructed additional rooms inside the upstairs portion of the residence to accommodate the drug operation, which included electrical wiring and ventilation systems that led to the attic.
Both Ruff and Jareo are charged with trafficking marijuana, possession with intent to sale, and maintaining a dwelling for the sale and manufacture of marijuana.
Additional charges could follow pending further investigation.
Both are being held in the Wake County Detention Center each under $201,000 bond. Their first court appearance is scheduled for Monday.