It happened Friday evening in the 1300 block of Ramsey Street in Fayetteville.
Witnesses said the woman ran off the road and into a parking lot.
The Good Samaritans saw that she wasn't responsive. They broke out a window and pulled her from the minivan just before it burst into flames.
The woman was taken to Cape Fear Valley Medical Center.
There's no word yet on the woman's identity or her condition.