Officials said a person who was driving a Chevy Tahoe had a medical condition around 1 p.m., which caused them to lose control of the vehicle. A tractor trailer subsequently hit the Tahoe from behind.
One adult and three children from the Tahoe were transported to Duke with non-life-threaten injuries. The driver of the tractor-trailer was treated at the scene.
Eyewitness video shows the aftermath of the crash.
The accident was said to have happened near mile marker 165.
Authorities say neither drugs nor alcohol were a factor in the crash, and no charges have been filed.