The city says enforcing panhandling laws is a public safety issue.
Three of the people arrested this week were picked up at the I-440 exit ramp at Hammond Road - a busy intersection.
"It's a traffic problem. Especially if you stop somebody and they're holding everybody up, that causes what you call road rage. So I can understand the police concern," offered Fred Hodges who lives in the area.
But some say the panhandlers are just trying to get money to survive - especially in the current economy.
The city requires panhandlers to have a permit and sets restrictions on where they can beg and when.