It happened on Nov. 16, 2018 in the 600 block of Dowd Street when a man was found shot on the sidewalk with gunshot wounds around 10:30 p.m.
18-year-old Zykari Rhone was pronounced dead at the scene.
Ricky Barfield, 25, was arrested on Aug. 21 on charges of murder, felony conspiracy, possession of a firearm by a convicted felon and possession of cocaine with the intent to manufacture, sell or deliver.
Robert Pridgen Jr., 28, was arrested on Sept. 11 on charges of murder and a misdemeanor probation violation.
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Ortez Richardson, 25, was arrested on Oct. 11 on charges of murder, possession of a stolen firearm, assault with a deadly weapon on a government official, possession of a firearm by a convicted felon and misdemeanor larceny.
Troy Howard, 18, was arrested on Oct. 18 charges of murder and failure to appear in court on an earlier felony drug charge.
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All four men were placed in Durham County Jail without bond.
Investigators are trying to identify a fifth person involved.
Durham police said the victim and men knew each other.
Anyone with information is asked to call Investigator Huelsman at (919) 560-4440, ext. 29341 or CrimeStoppers at (919) 683-1200. CrimeStoppers pays cash rewards for information leading to arrests in felony cases and callers never have to identify themselves.